![]() NC BioGrid combines computing and data resources into a unified environment for genomic research (data and computational grid). computational grid) over a collection of computers. The goal of is understanding protein folding, protein aggregation, and related diseases by utilizing idle CPU cycles (i. Particularly illustrative examples of working grid systems for computational biology are North Carolina BioGrid, caBig, and myGrid. ![]() Majority of grids today act as both data and computational grids. Computational grids, on the other hand, provide the ability to perform computations remotely, possibly in parallel, without the user having to know anything about networking and communication between the computers (distribution transparency). Some grid middleware has evolved to bind data resources scattered across a network into a unified environment to make it appear to the user as if all the data is stored locally on that user's desktop (data grids). In this regard it is useful to recall the context of their development and in particular the eroding distinction between data and computational grids. However, the discovery mode of many computational biology initiatives which favours the autonomous use of rapid prototyping environments by small groups or even individual researchers, which does not bode well with the predominant, heavier, distributed computational infrastructures available. Ĭomputational biology applications with large memory and CPU requirements have been a significant driving force behind grid development. The specific goal underlying the Grid concept is coordinated resource sharing and problem solving in dynamic, multi-institutional virtual organizations. Today, Grids seek to provide seamless, scalable, high-performance and secure mechanisms for locating and negotiating access to remote and possibly heterogeneous resources. The term 'grid' was coined in the mid-1990s and designates distributed computing infrastructures for science and engineering.
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